Podcast #31: Athletic Performance and Hypertrophy with Kiefer

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https://podcasts.apple.com/us/podcast/jacked-athlete-podcast/id1462537296?l=es


“Most individuals already have insulin resistance in their skeletal muscle tissue by the time they’re 20-25.”

“Basketball players… their endurance that they have to build up requires less carbohydrates…. a lineman, where they only have very short bursts of high output activity, so their diet is gonna be a little different.”

“You have to mobilize glycogen to get maximum hypertrophy signals… ingested glucose is not causing the same hypertrophy signaling.”


Post-Workout

“If you’re trying to refill glycogen, you’ve got a 30-minute window post-workout that’s optimal.”

“The earliest you’re gonna peak with protein synthesis (fractional synthesis rate)… that’s 4 hours out from your workout.”

Protein shake right after working out: “There’s no reason to… When you’re working out, protein breakdown and protein synthesis, both of those rates actually get much lower. They actually almost turn off during the training. Immediately after training, you get this exponential growth in the breakdown rate… There’s a very significant lag before the synthesis rate starts to pick up.”

“In all growth processes, especially in muscle, the breakdown rate has to peak before the synthesis rate can have a chance of peaking.”

“The peak of breakdown is directly related to the peak of the synthesis later.”

“An hour out, you shouldn’t interfere with the peak breakdown.”


Male/Female Differences in Glycogen

“For men with average testosterone levels, the more power and work you do, the more glycogen you burn.”

“If you walk around and you’re a male with average testosterone levels, you’re burning glycogen.”

“The curve for glycogen burn rate for women, stays really close to zero until they get around 80% VO2Max.”

Taking synthetic testosterone: “They will burn glycogen faster at lower power outputs… and testosterone allows their muscles to store glycogen at a slightly higher density so they also have more glycogen to burn.”

“The longer distances you go, women should start to have more and more advantages… women finish much closer to men at a marathon than they do at a 400m sprint… women finish almost equal when you start getting up into the ultramarathon territory.”

“Women would always need to be far more cognizant of their usable carbohydrate intake than men are most of the time.”


Hypertrophy

“What matters is total power output. Not total work. Not total volume. Those things are meaningless. It’s total power output.”

Low rep vs. High rep: “If those are identical for power outut, then you’ll get the same results.”

“On those higher rep sets, you are eventually acclimating the muscles to become more oxidative over time and you will slow hypertrophy. It’s unavoidable.”

“As you exercise that oxidative curve what you shorten is the glycolytic curve.” “As you overlap more in the oxidative state, you cannot access the second portion of the anaerobic window.”

“Newbies, super simple, if they’re going to failure, they’re gonna trigger growth. But that’s only gonna last about 3 months. And then they have to start taking into account those shorter, heavier rep ranges.”


How to do Repetitions

“There’s a huge anaerobic and signaling event at the turnaround. So your goal is to go through the turnaround and produce as much acceleration as possible… the faster you can do that turnaround at the bottom, the larger the overall growth signal that occurs.”

“Downregulating myostatin, upregulating mTor… those get their maximum stimulus at that turnaround.”


Splanchnic Bed

“Whenever insulin levels rise to a high threshold… then the majority of it (protein) gets pushed into the splanchnic bed. It doesn’t make it into the muscle tissue.”

“It’ll come back out once insulin levels drop.” “Whatever you stuffed in there, only half of it is useable for muscular synthesis.”

“It’s not such a bad thing cause you can overeat protein and then you basically have this huge reservoir that’s feeding all of the growth no matter whether you’re eating or not. So it’s quite advantageous.”


Caffeine

“Caffeine elevates AMPK really effectively especially in skeletal muscle tissue. So if you’re drinking a lot of caffeine all day long, you’re really stunting your hypertrophy goals.”

“Caffeine doesn’t cause an increase in cortisol release. That only happens with psychological stress experiments.”

1-hr before caffeine and 1-hr workout: “The caffeine’s effects will be almost gone by the end of the workout as far as AMPK elevation. And it’s totally fine because during the workout, both breakdown and synthesis processes are shut off anyway.”


Links

https://body.io/

https://carbnite.com/

https://carbbackloading.com/

Kiefer on Twitter

164 thoughts on “Podcast #31: Athletic Performance and Hypertrophy with Kiefer”

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  3. This was an incredibly insightful podcast, Jake! The points Kiefer made about insulin resistance hitting so early, even by 20-25, really resonated. It makes you rethink how early we should be focusing on metabolic health. I also found the distinctions between carbohydrate needs for different athletes, like basketball players versus linemen, fascinating and it provides such a practical takeaway for tailoring nutrition.

    The discussion on post-workout timing for glycogen replenishment and protein synthesis really challenged some long-held beliefs. It’s great to hear a deeper dive into the science behind why rushing that protein shake might not be as effective as once thought, especially with the breakdown rate needing to peak first. Thanks for sharing such valuable, evidence-based information that helps us all train smarter. It’s a goldmine for anyone serious about optimizing their athletic performance. Anyone looking to truly crunch the numbers on their fitness goals, might even find a financial calculator ba ii plus online useful for other aspects of their life too!

  4. This was a fantastic podcast, Jake! The insights from Kiefer about insulin resistance starting so early, especially for those 20-25, is a real eye-opener. I also found the distinction between carbohydrate needs for different athletes like basketball players versus linemen super valuable. And the myth-busting around post-workout protein shakes and the timing for optimal hypertrophy signals was mind-blowing – who knew protein synthesis takes so long to kick in after training? Definitely sharing this one with my workout buddies. It’s great to see such well-researched content that can really help people optimize their training and nutrition. I love discovering new resources and insights like these, it really helps to push the boundaries of understanding, much like how lockposters helps people explore large-scale printing!

  5. This was a seriously insightful podcast with Kiefer! The points about insulin resistance developing so early were eye-opening, and it’s fascinating how different athletic demands, like a basketball player versus a lineman, impact carbohydrate needs. I especially appreciated the discussion on glycogen mobilization for hypertrophy signals and the timing of post-workout nutrition. The idea that protein synthesis lags breakdown is a game-changer for how I’ve thought about immediate post-workout shakes. Thanks for sharing these valuable insights; it really makes you rethink some long-held beliefs about training and diet. You’ve definitely given me a lot to consider for optimizing my own routine, much like how a well-crafted AI Rap Video can make you rethink creative possibilities!

  6. This was an incredibly insightful podcast! Kiefer really dives deep into some nuanced aspects of athletic performance and hypertrophy that often get overlooked. The discussion around insulin resistance in young adults and the different carb needs for basketball players versus linemen was particularly eye-opening. And that breakdown on glycogen mobilization for maximum hypertrophy signals—fascinating!

    I especially appreciated the myth-busting about post-workout protein shakes. It’s great to hear a clear explanation of the protein breakdown and synthesis lag, making perfect sense of why that immediate shake isn’t as crucial as often believed. This kind of detail helps us all think more critically about our training and nutrition strategies. Really top-tier content, thanks for sharing!

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  11. This podcast with Kiefer is absolutely packed with fascinating insights! I really appreciated the deep dive into how carbohydrate timing and type affect athletic performance and hypertrophy – the distinction between basketball players and linemen was a great example. And the idea that most individuals already have insulin resistance by 20-25 is quite a wake-up call.

    I also found the discussion about post-workout nutrition, especially the timing of protein synthesis and glycogen refill, incredibly valuable. It really challenges some long-held beliefs about protein shakes immediately after a workout. Thanks for sharing this thought-provoking episode; it’s given me a lot to consider regarding optimizing my training and nutrition! I often find myself needing to Merge Image files for reference when diving into complex topics like this, so I appreciate clear, data-driven content.

  12. This was an incredibly insightful podcast! Kiefer really breaks down some crucial nuances in athletic performance and hypertrophy that often get overlooked. The discussion on insulin resistance in skeletal muscle tissue, even at a young age, was a real eye-opener. I especially appreciated the distinction between carbohydrate needs for basketball players versus linemen – it’s a great reminder that nutrition isn’t one-size-fits-all. And the detailed explanation about protein synthesis lag and the optimal post-workout window for glycogen refill challenges a lot of common gym wisdom. This podcast really offers a fantastic Split Image view into the science behind muscle growth. Definitely a must-listen for anyone serious about their training!

  13. This was such an insightful podcast, Jake! The points Kiefer made about insulin resistance in young adults and the tailored carb needs for different athletes (linemen vs. basketball players) really resonated. I found the discussion on glycogen mobilization for hypertrophy signals particularly fascinating – it’s a perspective I hadn’t considered in depth before.

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